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Journal Articles

A Mathematical Model of Maladaptive Inward Eutrophic Remodeling of Muscular Arteries in Hypertension

Alexander Rachev, Tarek Shazly
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2023, 145(1): 011012.
Paper No: BIO-22-1072
https://doi.org/10.1115/1.4055109
Published Online: September 1, 2022
View Article titled, A Mathematical Model of Maladaptive Inward Eutrophic Remodeling of Muscular Arteries in Hypertension
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Topics: Hoop stress, Pressure, Stress, Vessels, Dimensions, Wall thickness
Proceedings Papers

Fluid and Solid Mechanics in Stented Arteries

James E. Moore, Jr., Joel L. Berry, Emil Manoach, Alexander Rachev
Proc. ASME. IMECE99, Advances in Bioengineering, 71, November 14–19, 1999
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1999-0382
https://doi.org/10.1115/IMECE1999-0382
View Paper titled, Fluid and Solid Mechanics in Stented Arteries
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Topics: Biomechanics, Blood flow, Coronary arteries, Deflection, Deformation, Design, Flow (Dynamics), Flow visualization, Fluids, Linkages
Journal Articles

A Two-Dimensional Model of Hypertension-Induced Arterial Remodeling With Account for Stress Interaction Between Elastin and Collagen

Alexander Rachev, Tarek Shazly
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2020, 142(4): 041008.
Paper No: BIO-19-1325
https://doi.org/10.1115/1.4045116
Published Online: December 12, 2019
View Article titled, A Two-Dimensional Model of Hypertension-Induced Arterial Remodeling With Account for Stress Interaction Between Elastin and Collagen
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Topics: Biological tissues, Fibers, Pressure, Stress, Mechanical properties, Geometry, Constitutive equations
Proceedings Papers

A Combined Theoretical-Experimental Paradigm for Studying Mechanical Conditioning of Tissue Engineered Arteries

Julia Raykin, Alexander Rachev, Michael Zaucha, Rudolph L. Gleason, Jr.
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 75-76, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192746
https://doi.org/10.1115/SBC2008-192746
View Paper titled, A Combined Theoretical-Experimental Paradigm for Studying Mechanical Conditioning of Tissue Engineered Arteries
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Topics: Biological tissues, Bending (Stress), Biomechanics, Blood vessels, Shear stress, Stress, Biochemistry, Biology, Engineering disciplines, Materials science
Proceedings Papers

Response of Porcine Carotid Arteries to Independent Control of Medial Tensile Stresses and Shear Stress

Alexander Rachev, Zachary Dominguez, Raymond Vito
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 963-964, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192884
https://doi.org/10.1115/SBC2008-192884
View Paper titled, Response of Porcine Carotid Arteries to Independent Control of Medial Tensile Stresses and Shear Stress
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Topics: Blood flow, Carotid arteries, Geometry, Physiology, Pressure, Shear stress, Stress, Tension
Proceedings Papers

A Two Dimensional Phenomenological Model for Damage of Arteries

Alexander Rachev
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 201-202, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176442
https://doi.org/10.1115/SBC2007-176442
View Paper titled, A Two Dimensional Phenomenological Model for Damage of Arteries
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Topics: Damage, Biological tissues, Rupture, Failure, Strength (Materials), Stress, Aorta, Atherosclerosis, Cardiovascular system, Constitutive equations
Proceedings Papers

MMP-2 and -9 Collocate With High Stresses Predicted Using Heterogeneous Mechanical Model of Arteries

Yu Shin Kim, Zorina S. Galis, Alexander Rachev, Raymond P. Vito
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 223-224, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176575
https://doi.org/10.1115/SBC2007-176575
View Paper titled, MMP-2 and -9 Collocate With High Stresses Predicted Using Heterogeneous Mechanical Model of Arteries
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Topics: Stress, Biological tissues
Proceedings Papers

A Theoretical Simulation of Maladaptive Remodeling in Response to Hypertension

Aristotelis Agianniotis, Nikos Stergiopulos, Raymond P. Vito, Tarek Shazly, Alexander Rachev
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT28A004, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14462
https://doi.org/10.1115/SBC2013-14462
View Paper titled, A Theoretical Simulation of Maladaptive Remodeling in Response to Hypertension
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Topics: Simulation, Biological tissues, Blood vessels, Cardiovascular system, Continuum mechanics, Dimensions, Flow (Dynamics), Mechanical properties, Preservation, Pressure
Proceedings Papers

Active Stress in the Porcine Renal Artery

Boran Zhou, Alexander Rachev, Tarek Shazly
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT13A016, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14427
https://doi.org/10.1115/SBC2013-14427
View Paper titled, Active Stress in the Porcine Renal Artery
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Topics: Kidney, Stress, Surface mount components, Muscle, Biological tissues, Biophysics, Pressure
Proceedings Papers

Dynamic Instability of Arteries: Effects of Perivascular Tissue

Alexander Rachev, Rudolph Gleason
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1315-1316, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206467
https://doi.org/10.1115/SBC2009-206467
View Paper titled, Dynamic Instability of Arteries: Effects of Perivascular Tissue
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Topics: Biological tissues, Pressure, Physiology, Atherosclerosis, Bifurcation, Buckling, Dynamic stability, Equilibrium (Physics), Mechanical stability, Patents
Proceedings Papers

Active Axial Stress in Mouse Aorta

Aristotelis Agianniotis, Alexander Rachev, Nikos Stergiopulos
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 975-976, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80102
https://doi.org/10.1115/SBC2012-80102
View Paper titled, Active Axial Stress in Mouse Aorta
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Topics: Aorta, Stress, Surface mount components, Biological tissues, Mechanical behavior, Muscle, Vessels
Proceedings Papers

Calculation of the Outcomes of Adaptive and Maladaptive Remodeling of Arteries Subjected to Sustained Hypertension Using a 3D Two-Layered Model

Alexander Rachev, W. Robert Taylor, Raymond P. Vito
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 1011-1012, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80092
https://doi.org/10.1115/SBC2012-80092
View Paper titled, Calculation of the Outcomes of Adaptive and Maladaptive Remodeling of Arteries Subjected to Sustained Hypertension Using a 3D Two-Layered Model
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Topics: Blood flow, Coronary arteries, Geometry, Performance, Physiology, Pressure
Proceedings Papers

Buckling of Porcine Aorta Under Static and Dynamic Loading

Mobin Rastgar Agah, Kaveh Laksari, Kurosh Darvish, Alexander Rachev
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 287-288, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80931
https://doi.org/10.1115/SBC2012-80931
View Paper titled, Buckling of Porcine Aorta Under Static and Dynamic Loading
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Topics: Aorta, Buckling, Dynamic testing (Materials), Blood vessels, Atherosclerosis, Biomechanics, Blood, Blood flow, Cardiovascular system, Diseases
Proceedings Papers

A Structure-Based Model of Arterial Remodeling in Response to Sustained Hypertension

Alkiviadis Tsamis, Nikos Stergiopulos, Alexander Rachev
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1053-1054, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206338
https://doi.org/10.1115/SBC2009-206338
View Paper titled, A Structure-Based Model of Arterial Remodeling in Response to Sustained Hypertension
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Topics: Diseases, Pressure, Shear stress, Tension
Proceedings Papers

The Effects of Arterial Tissue Reorganization on the Geometrical Outputs of Pressure- and Flow-Induced Remodeling: A Theoretical Study

Tarek Shazly, Alexander Rachev
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 203-204, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80086
https://doi.org/10.1115/SBC2012-80086
View Paper titled, The Effects of Arterial Tissue Reorganization on the Geometrical Outputs of Pressure- and Flow-Induced Remodeling: A Theoretical Study
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Topics: Biological tissues, Flow (Dynamics), Pressure, Fibers, Mechanical properties, Muscle, Structural elements (Construction), Vessels, Bearings, Blood
Proceedings Papers

A Biomechanical Model for the Biaxial Effect of the Contraction of Muscle Cells

Aristotelis Agianniotis, Alexander Rachev, Nikos Stergiopulos
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 777-778, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53091
https://doi.org/10.1115/SBC2011-53091
View Paper titled, A Biomechanical Model for the Biaxial Effect of the Contraction of Muscle Cells
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Topics: Biomechanics, Muscle, Stress
Proceedings Papers

A Structure-Based Biomechanical Model for the Effect of Dissolution of Muscle Cells on Pig Arteries: Elastin Associated With Muscle and Extracellular Matrix

Aristotelis Agianniotis, Alexander Rachev, Nikos Stergiopulos
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 781-782, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53162
https://doi.org/10.1115/SBC2011-53162
View Paper titled, A Structure-Based Biomechanical Model for the Effect of Dissolution of Muscle Cells on Pig Arteries: Elastin Associated With Muscle and Extracellular Matrix
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Topics: Biomechanics, Muscle
Journal Articles

Are Geometrical and Structural Variations Along the Length of the Aorta Governed by a Principle of “Optimal Mechanical Operation”?

Alexander Rachev, Stephen Greenwald, Tarek Shazly
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2013, 135(8): 081006.
Paper No: BIO-12-1494
https://doi.org/10.1115/1.4024664
Published Online: June 12, 2013
View Article titled, Are Geometrical and Structural Variations Along the Length of the Aorta Governed by a Principle of “Optimal Mechanical Operation”?
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Topics: Aorta, Stress, Biological tissues, Pressure, Muscle, Physiology
Journal Articles

A Preliminary Analysis of the Data From an in Vitro Inflation-Extension Test Can Validate the Assumption of Arterial Tissue Elasticity

Alexander Rachev, Tarek Shazly
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. August 2013, 135(8): 084502.
Paper No: BIO-12-1507
https://doi.org/10.1115/1.4024665
Published Online: June 12, 2013
View Article titled, A Preliminary Analysis of the Data From an in Vitro Inflation-Extension Test Can Validate the Assumption of Arterial Tissue Elasticity
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Topics: Biological tissues, Elasticity, Errors, Stress, Pressure, Kidney
Journal Articles

Design and Fabrication of a Mechanically Matched Vascular Graft

Alexander Rachev, Luc Felden, David N. Ku
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. September 2011, 133(9): 091004.
https://doi.org/10.1115/1.4004533
Published Online: October 12, 2011
View Article titled, Design and Fabrication of a Mechanically Matched Vascular Graft
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Topics: Design, Pressure, Manufacturing