... mutagenesis [ 15 ]. The explosive pace of research involving new biologic tools for genetic engineering has put an increased demand on creation of biotechnologies that can deliver these constructs to target cells [ 1 – 6 ]. Historically, engineered viruses have been an attractive option for genetic...

... and pluripotency to differentiate into most of the cellular lineages [ 4 , 5 ]. Biomedical Biotechnology 08 10 2015 09 03 2016 Manuscript received October 8, 2015; final manuscript received March 9, 2016; published online May 6, 2016. Assoc. Editor: Feng Xu. 1 Corresponding...

.... Such a wound is referred to critical size defect, which was defined as the smallest intra osseous defect that would not heal spontaneously if left untreated during the lifetime of the animal [ 5 ]. Biomedical Biotechnology 15 09 2015 03 02 2016 Manuscript received September 15...

... of the intramolecular energy landscape. Manuscript received September 8, 2015; final manuscript received January 29, 2016; published online March 22, 2016. Assoc. Editor: Abraham Quan Wang. 08 09 2015 29 01 2016 Biotechnology Modeling and simulation Nanostructure Nanotechnolgy...

... 2015 Biomedical Biotechnology Fabrication Methods Growth Tools Multiple cell types, such as pancreatic cells, embryonic stem cells (ESCs), and cancerous cells, exist as 3D spheroids in vivo, which commonly scale from tens to hundreds of microns [ 1 – 4 ]. Cell spheroids...

... is maintained in three dimensions. Manuscript received May 11, 2015; final manuscript received July 27, 2015; published online September 29, 2015. Assoc. Editor: Ibrahim Ozbolat. 11 05 2015 27 07 2015 Biotechnology Three-dimensional (3D) bioprinting is emerging as a powerful...

... of biological materials including cells and nutrients. In addition to providing the architectural template, they attempt to mimic an in vivo 3D environment that can stimulate cells to secrete ECM in a more natural and efficient manner. Biomedical Biotechnology Materials Processes 04 06 2015...

... , “ Evaluation of 3D Printing and Its Potential Impact on Biotechnology and the Chemical Sciences ,” Anal. Chem. , 86 ( 7 ), pp. 3240 – 3253 . 10.1021/ac403397r [12] Lee , K. G. , Park , K. J. , Seok , S. , Shin , S. , Kim , D. H. , Park , J. Y. , Heo , Y. S. , Lee , S. J...

... of media in a matter of minutes. Biomedical Biotechnology Fabrication Methods Growth Tools The major goals of the field of regenerative medicine are to treat and restore function to damaged and dysfunctional tissue [ 1 ]. A major challenge in this field is to develop methodologies...

... April 12, 2015; final manuscript received April 16, 2015; published online September 29, 2015. Assoc. Editor: Abraham Quan Wang. 12 04 2015 16 04 2015 Biomedical Biotechnology Bioprinting is a promising technology in regenerating tissues and organs and has recently gained...

... of evidence suitable for legal proceedings. Biomedical Biotechnology Materials Methods Nanostructure Nanotechnolgy Particles Pharmaceuticals Tools Processes Forensic science, according to the California Criminalistics Institute, is defined as an application of the methods...

... of plasmonic NPs for molecule concentration and detection, which could inspire new Raman sensing devices for applications in microfluidics. Biotechnology Detection methods Electronic phenomena systems photonic Fabrication Fluidics Nanostructure Nanotechnolgy Growth Photonic phenomena systems...

...-mail:  jung.han@yale.edu e-mail:  jphu@umich.edu e-mail:  rong.fan@yale.edu 1 L. Han and J. Zhou contributed equally to this work. 02 02 2015 17 03 2015 06 08 2020 Biomedical Biotechnology Fabrication Nanostructure Growth Nanostructured semiconductors...

... with CSM. It is hypothesized that such a delivery device will greatly reduce any systemic toxicity and increase antitumor efficacy. This paper describes the methods for developing CSM and maintaining the integrity of CDDP NPs embedded in the CSM. Biomedical Biotechnology Drug delivery Materials...

..., while maintaining 78–91% viability. With these results, we submit the nanoinjection method using a silicon lance array as another promising particle delivery method for mammalian culture cells. Biotechnology Drug delivery Many methods to deliver foreign material into living animal cells...

... nanoparticles. Biomedical Biotechnology Materials Nanotechnolgy Processes Centrioles are tiny organelles lying adjacent to the nucleus of human and animal (eukaryotic) cells (see Fig. 1 ). Although their existence has been known for now over 100 years [ 1–7 ], centrioles have only recently...

... of biomedical devices. Biomedical Biotechnology Detection methods Methods Nanotechnolgy Tools When Richard Feynman was writing his paper titled “There's Plenty of Room at the Bottom: An Invitation to Enter a New Field of Physics” [ 1 ] presented at the American Physical Society annual meeting...

...: 978-1-4398-5953-7 Biomedical Biotechnology Detection methods Fabrication Imaging techniques Materials Nanotechnolgy Pharmaceuticals Structures Growth Processes Devices 09 02 2013 21 02 2013 Copyright © 2013 by ASME 2013 1949-2944/2013/3(4)/046501/2/ $0.00 ...