Abstract

During 1989 and 1990, the Civil Aeromedical Institute received specimens from 975 victims of fatal aircraft accidents. The maximum concentration of ethanol allowed under FAA regulations (0.04%, 40 mg/dL) was exceeded in 79 of these cases (8%). It was determined based on the distribution of ethanol in urine, vitreous humor, blood, and tissue that 21 of the positive cases (27%) were from postmortem alcohol production. Twenty-two of the positive cases (28%) were found to be from the ingestion of ethanol. In 36 cases (45%), no determination could be made regarding the origin of the ethanol. In two cases, postmortem alcohol production exceeded 0.15% (150 mg/dL).

The opinion held by some toxicologists that postmortem alcohol production can be inferred from the presence of acetaldehyde, acetone, butanol, and other volatiles was found to be incorrect. Several cases with postmortem ethanol had no other volatiles. Volatile compounds were found in several cases where no ethanol was present. In addition a case was found in which the relative ethanol concentrations in blood, bile, and vitreous humor were solely consistent with the ingestion of ethanol, but acetaldehyde, acetone, and 2-butanol were also found in blood. This clearly indicates that the presence or absence of other volatiles does not establish postmortem ethanol production.

References

1.
Corry
,
J. E. L.
, “
A Review Possible Sources of Ethanol Ante- and Post-mortem: Its Relationship to the Biochemistry and Microbiology of Decomposition
,”
Journal of Applied Bacteriology
 0021-8847, Vol.
44
,
1978
, pp.
1
-
56
.
2.
Stone
,
B. E.
and
Rooney
,
P. A.
, “
A Study Using Body Fluids to Determine Blood Alcohol
,”
Journal of Analytical Toxicology
 0146-4760, Vol.
8
,
1984
, pp.
95
-
96
.
3.
Nicloux
,
M.
, “
Dosage of Alcohol in Putrefied Blood and Tissues
,”
Comptes Rendue des Séances, Société de Biologie
(Paris), Vol.
121
,
1935
, pp.
1301
-
1309
.
4.
Nicloux
,
M.
, “
Neoformation of Ethyl Alcohol in Human Cadavers in View of Putrefaction
,”
Comptes Rendue des Séances, Société de Biologie
(Paris), Vol.
121
,
1936
, pp.
975
-
978
.
5.
Caplan
,
Y. H.
and
Levine
,
B.
, “
Vitreous Humor in the Evaluation of Postmortem Blood Ethanol Concentrations
,”
Journal of Analytical Toxicology
 0146-4760, Vol.
14
,
1990
, pp.
305
-
307
.
6.
Harper
,
D. R.
, “
A Comparative Study of the Microbiological Contamination of Postmortem Blood and Vitreous Humour Samples Taken for Ethanol Determination
,”
Forensic Science International
 0379-0738, Vol.
43
,
1989
, pp.
37
-
44
.
7.
Neil
,
P.
,
Mills
,
A. J.
, and
Prabhakaran
,
V. M.
, “
Evaluation of Vitreous Humor and Urine Alcohol Levels as Indices of Blood Alcohol Levels in 75 Autopsy Cases
,”
Canadian Society of Forensic Science
, Vol.
18
,
1985
, pp.
97
-
104
.
8.
Bogusz
,
M.
,
Guminska
,
M.
, and
Markiewicz
,
J.
, “
Studies of the Formation of Endogenous Ethanol in Blood Putrefying In Vitro
,”
Journal of Forensic Medicine
 0022-1171, Vol.
17
,
1970
, pp.
156
-
168
.
9.
Spitz
,
W. U.
and
Fisher
,
R. S.
,
Medicolegal Investigation of Death
,
Charles C Thomas
,
Springfield, IL
,
1980
, pp.
567
-
568
.
10.
Falconer
,
B.
and
Falconer
,
C.
, “
Postmortal Blood Alcohol in Various Parts of the Vascular System
,”
Blutalkohol
 0006-5250, Vol.
10
,
1973
, pp.
328
-
335
.
11.
Luvoni
,
R.
and
Marozzi
,
E.
, “
Ethyl Alcohol Distribution in The Various Organs and Fluids of Cadavers
,”
Journal of Forensic Medicine
 0022-1171,” Vol.
15
,
1968
, pp.
67
-
70
.
12.
Davis
,
G. L.
,
Leffert
,
R. L.
and
Rantanen
,
N. W.
, “
Putrefactive Ethanol Sources in Postmortem Tissues of Conventional and Germ-Free Mice
,”
Archives of Pathology
 0363-0153, Vol.
94
,
1972
, pp.
71
-
74
.
13.
Blume
,
P.
and
Lakatua
,
D. J.
, “
The Effect of Microbial Contamination of the Blood Sample on the Determination of Ethanol Levels in Serum
,”
American Journal of Clinical Pathology
 0002-9173, Vol.
60
,
1973
, pp.
700
-
702
.
14.
Russell
,
A. B.
, “
Post-Mortem Blood Alcohol Survey in Some Australian States
,”
The Medical Journal of Australia
, Vol.
2
,
1971
, pp.
948
-
951
.
15.
Blackmore
,
D. J.
, “
The Bacterial Production of Ethyl Alcohol
,”
Journal of the Forensic Science Society
, Vol.
8
,
1968
, pp.
73
-
76
.
16.
Biasotti
,
A.
and
Valentine
,
T.
, “
Blood Alcohol Concentration Determined from Urine Samples As Practical Equivalent or Alternative to Blood and Breath Alcohol Tests
,”
Journal of Forensic Sciences
 0022-1198, Vol.
30
, No.
1
,
1985
, p. 194.
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