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Journal Articles

Enhancing Inhalation Drug Delivery: A Comparative Study and Design Optimization of a Novel Valved Holding Chamber

Shahab Azimi, Siamak Arzanpour
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2024, 146(4): 041002.
Paper No: BIO-23-1276
https://doi.org/10.1115/1.4064436
Published Online: February 7, 2024
View Article titled, Enhancing Inhalation Drug Delivery: A Comparative Study and Design Optimization of a Novel Valved Holding Chamber
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Topics: Design, Optimization, Particulate matter, Simulation, Valves, Drugs, Engineering prototypes, Flow (Dynamics), Drug delivery systems
Journal Articles

A First Step Toward a Family of Morphed Human Body Models Enabling Prediction of Population Injury Outcomes

Karl-Johan Larsson, Jonas Östh, Johan Iraeus, Bengt Pipkorn
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2024, 146(3): 031008.
Paper No: BIO-23-1197
https://doi.org/10.1115/1.4064033
Published Online: January 29, 2024
View Article titled, A First Step Toward a Family of Morphed Human Body Models Enabling Prediction of Population Injury Outcomes
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Topics: Optimization, Performance, Risk, Simulation, Vehicles, Weight (Mass), Wounds, Fracture (Process), Fracture (Materials), Metamodeling
Includes: Supplementary data
Journal Articles

An In Silico Model for Predicting the Efficacy of Edge-to-Edge Repair for Mitral Regurgitation

Junichi Ooida, Naoki Kiyohara, Hironaga Noguchi, Yuichiro Oguchi, Kohei Nagane, Takuya Sakaguchi, Gakuto Aoyama, Fumimasa Shige, James V. Chapman, Masahiko Asami, Klaus Fuglsang Kofoed, Michael Huy Cuong Pham, Koshiro Suzuki
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2024, 146(2): 021004.
Paper No: BIO-23-1176
https://doi.org/10.1115/1.4064055
Published Online: December 12, 2023
View Article titled, An In Silico Model for Predicting the Efficacy of Edge-to-Edge Repair for Mitral Regurgitation
Open the PDF for An In Silico Model for Predicting the Efficacy of Edge-to-Edge Repair for Mitral Regurgitation in another window
Topics: Deformation, Hemodynamics, Simulation, Valves, Maintenance, Optimization, Pressure
Journal Articles

Performance Optimization of a Microfluidic Virus Detection Cartridge: A Numerical and Experimental Study

Enes Burak Şenel, Bilal Kizilelma, Enes Tamdoğan, Mustafa Yorulmaz
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2023, 145(10): 101010.
Paper No: BIO-23-1058
https://doi.org/10.1115/1.4062850
Published Online: July 14, 2023
View Article titled, Performance Optimization of a Microfluidic Virus Detection Cartridge: A Numerical and Experimental Study
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Topics: Flow (Dynamics), Geometry, Microchannels, Microfluidics, Optimization, Biosensors, Optical microscopy
Journal Articles

A Novel Evaluation Index and Optimization Method for Ankle Rehabilitation Robots Based on Ankle-Foot Motion

Jianjun Zhang, Zhihao Ma, Jun Wei, Shuai Yang, Chenglei Liu, Shijie Guo
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2023, 145(5): 051006.
Paper No: BIO-22-1192
https://doi.org/10.1115/1.4056479
Published Online: February 1, 2023
View Article titled, A Novel Evaluation Index and Optimization Method for Ankle Rehabilitation Robots Based on Ankle-Foot Motion
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Topics: Optimization, Robots, Trajectories (Physics), Design, Engineering prototypes, Simulation
Journal Articles

Tibial Strains During Prolonged Downhill Running: A Finite Element Analysis

Arash Khassetarash, Ifaz Haider, Michael Baggaley, W. Brent Edwards
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2023, 145(4): 041007.
Paper No: BIO-22-1141
https://doi.org/10.1115/1.4055756
Published Online: December 5, 2022
View Article titled, Tibial Strains During Prolonged Downhill Running: A Finite Element Analysis
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Topics: Bone, Fatigue, Finite element analysis, Finite element model, Muscle, Stress, Modeling, Boundary-value problems, Optimization, Computerized tomography
Includes: Supplementary data
Journal Articles

Dots-on-Plots: A Web Application to Analyze Stress–Strain Curves From Tensile Tests of Soft Tissue

Derek Q. Nesbitt, Miranda L. Nelson, Kyle S. Shannon, Trevor J. Lujan
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. February 2023, 145(2): 024504.
Paper No: BIO-22-1124
https://doi.org/10.1115/1.4055593
Published Online: November 3, 2022
View Article titled, Dots-on-Plots: A Web Application to Analyze Stress–Strain Curves From Tensile Tests of Soft Tissue
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Topics: Mechanical properties, Stress, Stress-strain curves, Soft tissues, Shapes, Optimization, Damage, Errors
Journal Articles

Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning

Ali Behrangzade, Bruce R. Simon, William R. Wagner, Jonathan P. Vande Geest
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2023, 145(2): 021002.
Paper No: BIO-22-1025
https://doi.org/10.1115/1.4055563
Published Online: October 6, 2022
View Article titled, Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning
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Topics: Aorta, Fluids, Optimization, Permeability, Simulation, Flow (Dynamics), Thrombosis, Geometry, Finite element analysis, Platelets
Journal Articles

Estimation of Simulated Left Ventricle Elastance Using Lumped Parameter Modelling and Gradient-Based Optimization With Forward-Mode Automatic Differentiation Based on Synthetically Generated Noninvasive Data

Ryno Laubscher, Johan Van Der Merwe, Philip Herbst, Jacques Liebenberg
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2023, 145(2): 021008.
Paper No: BIO-22-1179
https://doi.org/10.1115/1.4055565
Published Online: October 6, 2022
View Article titled, Estimation of Simulated Left Ventricle Elastance Using Lumped Parameter Modelling and Gradient-Based Optimization With Forward-Mode Automatic Differentiation Based on Synthetically Generated Noninvasive Data
Open the PDF for Estimation of Simulated Left Ventricle Elastance Using Lumped Parameter Modelling and Gradient-Based Optimization With Forward-Mode Automatic Differentiation Based on Synthetically Generated Noninvasive Data in another window
Topics: Cardiovascular system, Errors, Flow (Dynamics), Optimization, Pressure, Sensitivity analysis, Valves
Journal Articles

Sensitivity of Internal Tibial Forces and Moments to Static Optimization Moment Constraints at the Subtalar and Ankle Joints

Michael Baggaley, Timothy R. Derrick, W. Brent Edwards
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2023, 145(1): 011008.
Paper No: BIO-22-1082
https://doi.org/10.1115/1.4055036
Published Online: August 19, 2022
View Article titled, Sensitivity of Internal Tibial Forces and Moments to Static Optimization Moment Constraints at the Subtalar and Ankle Joints
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Topics: Muscle, Optimization, Structural mechanics, Dynamics (Mechanics), Knee
Journal Articles

Enhancing the Biofidelity of an Upper Cervical Spine Finite Element Model Within the Physiologic Range of Motion and Its Effect on the Full Ligamentous Neck Model Response

Prasannaah Hadagali, Duane S. Cronin
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2023, 145(1): 011007.
Paper No: BIO-22-1079
https://doi.org/10.1115/1.4055037
Published Online: August 19, 2022
View Article titled, Enhancing the Biofidelity of an Upper Cervical Spine Finite Element Model Within the Physiologic Range of Motion and Its Effect on the Full Ligamentous Neck Model Response
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Topics: Cervical spine, Finite element model, Kinematics, Optimization, Physiology, Rotation, Biological tissues
Includes: Supplementary data
Journal Articles

Model-Based Acetabular Cup Orientation Optimization Based on Minimizing the Risk of Edge-Loading and Implant Impingement Following Total Hip Arthroplasty

Behzad Danaei, John McPhee
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2022, 144(11): 111008.
Paper No: BIO-22-1041
https://doi.org/10.1115/1.4054866
Published Online: July 14, 2022
View Article titled, Model-Based Acetabular Cup Orientation Optimization Based on Minimizing the Risk of Edge-Loading and Implant Impingement Following Total Hip Arthroplasty
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Topics: Arthroplasty, Optimization, Risk, Dislocations
Journal Articles

Motion-Based Ground Reaction Forces and Moments Prediction Method for Interaction With a Moving and/or Non-Horizontal Structure

Louise Demestre, Pauline Morin, François May, Nicolas Bideau, Guillaume Nicolas, Charles Pontonnier, Georges Dumont
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. November 2022, 144(11): 114504.
Paper No: BIO-22-1009
https://doi.org/10.1115/1.4054835
Published Online: July 14, 2022
View Article titled, Motion-Based Ground Reaction Forces and Moments Prediction Method for Interaction With a Moving and/or Non-Horizontal Structure
Open the PDF for Motion-Based Ground Reaction Forces and Moments Prediction Method for Interaction With a Moving and/or Non-Horizontal Structure in another window
Topics: Biomechanics, Dynamics (Mechanics), Equilibrium (Physics), Errors, Optimization, Shapes, Steel
Includes: Supplementary data
Journal Articles

Visions of TAVR Future: Development and Optimization of a Second Generation Novel Polymeric TAVR

Brandon Kovarovic, Ryan Helbock, Kyle Baylous, Oren M. Rotman, Marvin J. Slepian, Danny Bluestein
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2022, 144(6): 061008.
Paper No: BIO-21-1420
https://doi.org/10.1115/1.4054149
Published Online: April 6, 2022
View Article titled, Visions of TAVR Future: Development and Optimization of a Second Generation Novel Polymeric TAVR
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Topics: Design, Optimization, Stents, Valves, Stress, Shapes, Durability, Biological tissues, Polymers
Journal Articles

Different Phases in Manual Materials Handling Have Different Performance Criteria: Evidence From Multi-Objective Optimization

Size Zheng, Tong Li, Qingguo Li, Tao Liu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2022, 144(9): 091004.
Paper No: BIO-21-1277
https://doi.org/10.1115/1.4054150
Published Online: March 30, 2022
View Article titled, Different Phases in Manual Materials Handling Have Different Performance Criteria: Evidence From Multi-Objective Optimization
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Topics: Errors, Knee, Materials handling, Optimal control, Optimization, Pareto optimization, Stability, Torque, Kinematics, Rotation
Journal Articles

A Musculoskeletal Multibody Algorithm Based on a Novel Rheonomic Constraints Definition Applied to the Lower Limb

Alessandro Ruggiero, Alessandro Sicilia
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2022, 144(8): 081010.
Paper No: BIO-21-1367
https://doi.org/10.1115/1.4053874
Published Online: March 11, 2022
View Article titled, A Musculoskeletal Multibody Algorithm Based on a Novel Rheonomic Constraints Definition Applied to the Lower Limb
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Topics: Algorithms, Constraint equations, Dynamics (Mechanics), Muscle, Musculoskeletal system, Optimization, Lubrication, Tribology, Kinematics, Matlab
Includes: Supplementary data
Journal Articles

Tuning the Pennes Perfusion Rate to Model Large Vessel Cooling Effects in Hepatic Radiofrequency Ablation

Nikhil Vaidya, Marco Baragona, Valentina Lavezzo, Ralph Maessen, Karen Veroy
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. August 2022, 144(8): 084506.
Paper No: BIO-21-1368
https://doi.org/10.1115/1.4053909
Published Online: March 11, 2022
View Article titled, Tuning the Pennes Perfusion Rate to Model Large Vessel Cooling Effects in Hepatic Radiofrequency Ablation
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Topics: Biological tissues, Blood vessels, Cooling, Errors, Liver, Radiofrequency ablation, Vessels, Simulation, Temperature, Optimization
Journal Articles

A Two-Experiment Approach to Scaling in Biomechanics

Raul Ochoa-Cabrero, Teresa Alonso-Rasgado, Keith Davey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2022, 144(8): 081004.
Paper No: BIO-21-1321
https://doi.org/10.1115/1.4053627
Published Online: February 21, 2022
View Article titled, A Two-Experiment Approach to Scaling in Biomechanics
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Topics: Approximation, Biomechanics, Bone, Composite materials, Errors, Finite element model, Space, Statistical analysis, Microscopes, Experimental design
Journal Articles

Erratum: “Internal Tibial Forces and Moments During Graded Running” [ASME J. Biomech. Eng., 2021, 144 (1), p. 011009; DOI: 10.1115/1.4051924 ]

Michael Baggaley, Timothy R. Derrick, Gianluca Vernillo, Guillaume Y. Millet, W. Brent Edwards
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Errata
J Biomech Eng. July 2022, 144(7): 077001.
Paper No: BIO-21-1434
https://doi.org/10.1115/1.4053423
Published Online: February 15, 2022
View Article titled, Erratum: “Internal Tibial Forces and Moments During Graded Running” [ASME J. Biomech. Eng., 2021, 144 (1), p. 011009; DOI: 10.1115/1.4051924 ]
Open the PDF for Erratum: “Internal Tibial Forces and Moments During Graded Running” [ASME J. Biomech. Eng., 2021, 144 (1), p. 011009; DOI: 10.1115/1.4051924 ] in another window
Topics: Errors, Knee, Optimization
Journal Articles

A Computationally Efficient Lower Limb Finite Element Musculoskeletal Framework Directly Driven Solely by Inertial Measurement Unit Sensors

Sentong Wang, Kazunori Hase, Susumu Ota
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2022, 144(5): 051011.
Paper No: BIO-21-1235
https://doi.org/10.1115/1.4053211
Published Online: January 21, 2022
View Article titled, A Computationally Efficient Lower Limb Finite Element Musculoskeletal Framework Directly Driven Solely by Inertial Measurement Unit Sensors
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Topics: Contact mechanics, Finite element analysis, Kinematics, Knee, Muscle, Musculoskeletal system, Sensors, Optimization, Measurement units and standards, Cartilage