A series of dwell-fatigue tests were conducted on nanosilver sintered lap shear joint at elevated temperatures from 125 °C to 325 °C. The effects of temperature and loading conditions on dwell-fatigue behavior of nanosilver sintered lap shear joint were systematically studied. With higher temperature and longer dwell time, creep played a more important part in dwell-fatigue tests. Creep strain accumulated during maximum shear stress hold was found partly recovered by the subsequent cyclic unloading. Both the fracture mode and silver particle growth pattern were characterized by X-ray tomography system and scanning electron microscope (SEM). The mean shear strain rate synthesized the effects of various factors, such as temperature, shear stress amplitude, mean shear stress, and dwell time, by which the fatigue and dwell-fatigue life of nanosilver sintered lap shear joint could be well predicted within a factor of two.